Hematological parameters and transaminases related to the dengue virus in patients treated at the Liberlab Clinical Laboratory

Abstract

Dengue is a mosquito-borne viral disease most common, with a significant global disease burden. This study aimed to evaluate hematological and transaminase parameters related to the dengue virus in patients treated at the Liberlab clinical laboratory. The methodology used was a non-experimental, retrospective, descriptive, cross-sectional design, with 37 adult patients with dengue ranging in age from 18 to 65. Statistical analysis was performed using SPSS 27. The results obtained were mostly normal hematological values; 89.2% had normal hemoglobin levels, although 8.1% presented anemia, normal white blood cell count in 70.3%, and 18.9% showed leukopenia. Platelets were normal in 62.2%, with thrombocytopenia observed in 37.8%; Regarding transaminases, abnormalities in aspartate aminotransferase were evident in 62.2% and alanine aminotransferase in 59.5%; however, both parameters did not demonstrate a statistically significant correlation. They concluded that hematological alterations such as thrombocytopenia and leukopenia exist in addition to elevated transaminases, however, they did not show a significant association. However, these parameters can be considered as complementary indicators for the diagnosis and monitoring of patients with dengue.