Antimicrobial resistance of microorganisms in urine cultures from gynecological patients

Abstract

Antimicrobial resistance in microorganisms is primarily caused by the inappropriate use of antimicrobials, which has led to situations where treatment fails to effectively address the infection. In gynecological patients, urinary tract infections are highly prevalent, and antibiotics are the primary treatment; in certain cases, this has contributed to an increase in antimicrobial resistance. therefore, this study sought to evaluate the antimicrobial resistance of these microorganisms associated with the infection, using positive urine cultures—that is, those in which bacterial growth was observed. Notably, Gram-negative bacteria such as Escherichia coli, which had the highest growth rate, were identified, along with Klebsiella pneumoniae and one case of Enterobacter cloacae. Consequently, the type of resistance for each was determined, with the broad-spectrum beta-lactamase-producing resistance mechanism standing out for E. coli and K. pneumoniae, which exhibit resistance primarily to cephalosporins. On the other hand, the AmpC-type induced beta-lactamase resistance mechanism was also present, which refers to resistance to cephalosporins as well as ampicillin and amoxicillin.