Pseudomonas aeruginosa in skin infections of diabetic patients

Abstract

Diabetes mellitus is a metabolic disease that affects multiple organs, including the skin, predisposing patients to develop skin lesions that, due to their difficulty in healing, can become foci of infection. Colonization by microorganisms such as gram-positive bacteria and gram-negative bacteria such as Pseudomonas aeruginosa increases the risk of serious complications, including gangrene, osteomyelitis, and sepsis. Early identification of pathogens in these lesions is essential to improve clinical management and prevent complications in the diabetic population. 25 patients were analyzed, where a sample of the purulent skin lesion was taken in diabetic patients. A microbiological culture was then performed for the identification and isolation of Pseudomonas aeruginosa. Finally, an antibiogram was carried out to determine the levels of susceptibility and/or resistance to different antibiotics. The results showed that Pseudomonas aeruginosa was the most frequently isolated microorganism (48%). It was followed by (Staphylococcus aureus) (24%), Escherichia coli (20%), and (Klebsiella pneumoniae) (8%). In the antibiogram of Pseudomona aeruginosa, greater sensitivity was observed against third-generation cephalosporins and meropenem (83.3%), while the highest resistance corresponded to imipenem (33.3%).